Research
My research has three themes. Each theme lists the related publications.
3D-Printed Composite Scaffolds
Eggshells are made mostly of calcium carbonate. I developed 3D-printed thermoplastic scaffolds reinforced with eggshell microparticles for bone tissue engineering. I evaluated the scaffold architecture, the bioactivity, and the response of osteogenic cells in vitro.
Publications
- Eggshell-Based Unconventional Biomaterials for Medical ApplicationsAdvanced NanoBiomed Research, 2025, 5(2), 2400120.
- 3D Printed Eggshell Microparticle-Laden Thermoplastic Scaffolds for Bone Tissue EngineeringACS Applied Materials & Interfaces, 2024, 16(26), 32957–32970.
Videos
Oxygen-Generating Biomaterials Ongoing
Cells inside an engineered tissue can run short of oxygen before blood vessels reach them. I work on scaffolds that generate oxygen to support cells during this period. I am developing two formats: 3D-printed scaffolds and origami-inspired paper-based scaffolds. The work combines scaffold fabrication with cell studies under hypoxic culture. Preliminary work also includes endothelial-compatibility studies with human umbilical vein endothelial cells (HUVECs). This work is ongoing and unpublished.
Publications
- Oxygen-Generating Scaffolds: One Step Closer to the Clinical Translation of Tissue Engineered ProductsChemical Engineering Journal, 2023, 455, 140783.
Hydrogels & Paper-Hydrogel Constructs
I contributed to two published hydrogel studies. The first developed photocrosslinkable hydrogels from human-derived gelatin for tissue engineering. The second developed a sprayable hydrogel-based wound dressing and tested it in an in vitro model.
Ongoing I also work on origami-inspired paper-hydrogel scaffolds. The aim is a foldable scaffold architecture that combines paper with hydrogel. These scaffolds are also part of my oxygen-generating work. This work is ongoing and unpublished.
Publications
- Development of a Sprayable Hydrogel-Based Wound Dressing: An In Vitro ModelGels, 2024, 10(3), 176.
- Development of Human-Derived Photocrosslinkable Gelatin Hydrogels for Tissue EngineeringBiomacromolecules, 2024, 25(1), 165–176.
Other Projects
Paper-based diagnostic platforms
I designed and evaluated paper-based lateral-flow and vertical-flow assay platforms as part of collaborative projects in the lab.
Earlier Work
Undergraduate research (B.S., Yıldız Technical University; project at Marmara University, NBUAM)
As an undergraduate student researcher at the Center for Nanotechnology & Biomaterials Applications and Research (NBUAM) at Marmara University, I developed drug-encapsulated biodegradable scaffolds for the treatment of hidradenitis suppurativa. The work was published in MRS Bulletin in 2024, with me as first author. It received a Best Paper Award at the Academy of Romanian Scientists International Scientific Conference in 2021.
In 2018, I was an intern in the Bioprinting Lab of the Nanotechnology Research and Application Center (SUNUM) at Sabancı University. I designed bifurcated soft-tissue and vascular geometries in Rhinoceros and supported FRESH bioprinting workflows.
In 2019, I received a TÜBİTAK 2209-A undergraduate research grant for the project "Development of Bioink for Bone Tissue Engineering Applications". I presented this and related 3D printing work at the 4th International Congress on 3D Printing Technologies and Digital Industry in 2019. The presentations are listed on the Publications page.
Publications
- Novel Production Strategy of Drug-Encapsulated Biodegradable Scaffolds for Remediation of Hidradenitis SuppurativaMRS Bulletin, 2024, 49(11), 1100–1111.